diff --git a/packages/babel-plugin-transform-es2015-modules-amd/src/index.js b/packages/babel-plugin-transform-es2015-modules-amd/src/index.js
index aaf1773048..a6a58ec390 100644
--- a/packages/babel-plugin-transform-es2015-modules-amd/src/index.js
+++ b/packages/babel-plugin-transform-es2015-modules-amd/src/index.js
@@ -128,13 +128,15 @@ export default function({ types: t }) {
           factory.expression.body.directives = node.directives;
           node.directives = [];
 
-          node.body = [
+          node.body = [];
+
+          path.pushContainer("body", [
             buildDefine({
               MODULE_NAME: moduleName,
               SOURCES: sources,
               FACTORY: factory,
             }),
-          ];
+          ]);
         },
       },
     },
diff --git a/packages/babel-plugin-transform-es2015-modules-amd/test/fixtures/regression/4192/actual.js b/packages/babel-plugin-transform-es2015-modules-amd/test/fixtures/regression/4192/actual.js
new file mode 100644
index 0000000000..ea9b101e1c
--- /dev/null
+++ b/packages/babel-plugin-transform-es2015-modules-amd/test/fixtures/regression/4192/actual.js
@@ -0,0 +1 @@
+export default function () {}
diff --git a/packages/babel-plugin-transform-es2015-modules-amd/test/fixtures/regression/4192/expected.js b/packages/babel-plugin-transform-es2015-modules-amd/test/fixtures/regression/4192/expected.js
new file mode 100644
index 0000000000..dd662419eb
--- /dev/null
+++ b/packages/babel-plugin-transform-es2015-modules-amd/test/fixtures/regression/4192/expected.js
@@ -0,0 +1,9 @@
+define(["exports"], function (exports) {
+  "use strict";
+
+  Object.defineProperty(exports, "__esModule", {
+    value: true
+  });
+
+  exports["default"] = function () {};
+});
diff --git a/packages/babel-plugin-transform-es2015-modules-amd/test/fixtures/regression/4192/options.json b/packages/babel-plugin-transform-es2015-modules-amd/test/fixtures/regression/4192/options.json
new file mode 100644
index 0000000000..5fa9737651
--- /dev/null
+++ b/packages/babel-plugin-transform-es2015-modules-amd/test/fixtures/regression/4192/options.json
@@ -0,0 +1,7 @@
+{
+  "plugins": [
+    "external-helpers",
+    "transform-es2015-modules-amd",
+    "transform-es3-member-expression-literals"
+  ]
+}
diff --git a/packages/babel-plugin-transform-es2015-modules-umd/test/fixtures/regression/4192/actual.js b/packages/babel-plugin-transform-es2015-modules-umd/test/fixtures/regression/4192/actual.js
new file mode 100644
index 0000000000..ea9b101e1c
--- /dev/null
+++ b/packages/babel-plugin-transform-es2015-modules-umd/test/fixtures/regression/4192/actual.js
@@ -0,0 +1 @@
+export default function () {}
diff --git a/packages/babel-plugin-transform-es2015-modules-umd/test/fixtures/regression/4192/expected.js b/packages/babel-plugin-transform-es2015-modules-umd/test/fixtures/regression/4192/expected.js
new file mode 100644
index 0000000000..c7ae2e346b
--- /dev/null
+++ b/packages/babel-plugin-transform-es2015-modules-umd/test/fixtures/regression/4192/expected.js
@@ -0,0 +1,21 @@
+(function (global, factory) {
+  if (typeof define === "function" && define.amd) {
+    define(["exports"], factory);
+  } else if (typeof exports !== "undefined") {
+    factory(exports);
+  } else {
+    var mod = {
+      exports: {}
+    };
+    factory(mod.exports);
+    global.actual = mod.exports;
+  }
+})(this, function (exports) {
+  "use strict";
+
+  Object.defineProperty(exports, "__esModule", {
+    value: true
+  });
+
+  exports["default"] = function () {};
+});
\ No newline at end of file
diff --git a/packages/babel-plugin-transform-es2015-modules-umd/test/fixtures/regression/4192/options.json b/packages/babel-plugin-transform-es2015-modules-umd/test/fixtures/regression/4192/options.json
new file mode 100644
index 0000000000..540e8e1b3e
--- /dev/null
+++ b/packages/babel-plugin-transform-es2015-modules-umd/test/fixtures/regression/4192/options.json
@@ -0,0 +1,7 @@
+{
+  "plugins": [
+    "external-helpers",
+    "transform-es2015-modules-umd",
+    "transform-es3-member-expression-literals"
+  ]
+}